Research

Research is integral to the ethos of the department and each faculty member is actively pursuing AFMRC and departmental research projects. Undergraduate students are encouraged and assisted in applying for ICMR short term projects. The facilities of Electron Microscopy, Immuno-histochemistry and Molecular Pathology are being used in this direction.

Research Topics

• Study of response & resistance to Imatinib on CML patients by quantitative PCR for Bcr Abl.- Col J Kotwal
• Role of clonality studies as an ancillary technique in lymphoproliferative disorders. PW Col RB Batra
• D2-40 immunostaining for lymphangiogenesis and lymphatic emboli and its association with HER-2/neu overexpression in breast carcinomas. PW- Col V Srinivas
• Aberrant Immunophenotypic Expression in Acute Leukemias: A Clinicopathologic Study using Flow Cytometer. PW- Lt Col A Malik
• A study of the histomorphologic prognostic markers and proliferative index with Genetic factors associated with favourable therapeutic outcomes in diffusely infiltrating gliomas PW- Lt Col P Deb
• The role of cytokines gene polymorphisms and the cytokine inducing molecule NFκB in the pathogenesis of psoriasis. PW- Lt Col N Moorchung
• Prospective application of a multiplex RT-PCR assay for the detection of balanced translocations in acute leukemia. PW - Col Jyoti Kotwal

Future Research Plans

• Flow cytometric analysis of NHL using FNAC and Fresh tissue biopsy material. A pilot Study.
• Analysis of platelet activation factors in severe sepsisand sepsis related MOD by flow-cytometric studies and its evaluation with currentprognostic scoring systems. A pilot Study. PW - Surg Cdr V Manu
• Spectrum of nephrotic syndrome and podocytopathies: study of podocyte associated markers in renal biopsies. PW - Lt Col S Badwal
• Role of immunohistochemistry in differentiating muscularis mucosae and muscularis propria as an aid to accurate staging of invasive transitional cell carcinoma of urinary bladder: a pilot study. PW- Wg Cdr P Kinra
• Study of the significance of mesangioproliferative changes in glomerulopathies in children
• A correlative study of clinicopathological and immunophenotypic features of mesenchymal tumors of GIT
• To study the clnicopathological profile of patients of interstitial lung disease admitted to a tertiary care chest hospital
• A study of p53,BCL-2, MIB-1in histopathogenesis of psoriasis vulgaris
• Histological comparison between updated Sydney System and OLGA system in chronic gastritis
• Expression of ER, PR, Her2/Neu and MIB-1 index in meningiomas
• Expression of Caspases 8 and Caspases 9 in DLBCL
• etection of HPV by gene amplification technique using PCR and its correlation with gynecologic examination and cytologic findings
• Role Of Nf Kappa B In The Pathogenesis Of Psoriasis
• Correlation Of Histopathological Features With Proliferation Index And Loss Of Heterozygosity 1p/19q Of Diffusely Infiltrating Gliomas
• To Study The Clinicopathological Features Of Patients With Haemophagocytosis
• A Study Of Prevelence Of Aspirin And Clopidogrel Resistance In Cardiac Patients
• Study Of DNA Methylation Pattern In Promoter Regions Of P 15 P 16 & E- Cadherin Gene In Cervical Scrapings
•  Evaluation Of Fascin-1 Expression In Transitional Cell Carcinomas Of Urinary Bladder As A Marker Of Invasion
•  Study Of Cervical Cytology And Incidence Of Human Papilloma Virus In Women Infected With The Human Immunodeficiency Virus